A 834735( A-834735 | A834735 )

Catalog No. M16446 CAS No. 895155-57-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

A 834735
Note

Research use only, not for human use.
Brief Description

A potent, nonselective, brain penetrant, full agonist at both the central CB1 and peripheral CB2 receptors with Ki of 4.6 and 0.31 nM, respectively.
Description

A potent, nonselective, brain penetrant, full agonist at both the central CB1 and peripheral CB2 receptors with Ki of 4.6 and 0.31 nM, respectively; reverses thermal hyperalgesia without adverse side effects in a rat neuropathic pain model.
In Vitro

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In Vivo

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Synonyms

A-834735 | A834735
Pathway

GPCR/G Protein
Target

Cannabinoid Receptor
Recptor

Cannabinoid Receptor
Research Area

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Indication

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CAS Number

895155-57-4
Formula Weight

339.5
Molecular Formula

C22H29NO2
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(C1=CN(CC2CCOCC2)C3=C1C=CC=C3)C4C(C)(C)C4(C)C
Chemical Name

[1-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)-methanone

1. Chin CL, et al. Br J Pharmacol. 2008 Jan;153(2):367-79. 2. Grim TW, et al. J Pharmacol Exp Ther. 2016 Nov;359(2):329-339.

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